ACTRA

Australasian College of Toxicology and

Risk Assessment

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June 2009 E-Newsletter

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Member news…

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Editor’s Note

ACTRA welcomes comments on any aspect of the e-newsletter. Please feel free to share suggestions or news, write letters to the editor or comment on articles presented. Your feedback is important to us!

 

Positions Vacant – Feel free to advertise positions in this newsletter. The dates for publication follow.

 

This is your newsletter!!

Please send contributions and Calendar notices to the Secretariat actra@meetingsfirst.com.au or editor jfrangos@bigpond.com

 

Submission deadlines
Issue 3: 21st August
Issue 4: 30th October

 

Submission rules

Publication of any material submitted to the ACTRA Newsletter will be the sole discretion of ACTRA. ACTRA reserves the right to make amendments to the submission prior to publication, or to refuse publication.

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President’s Report

Welcome to the second ACTRA newsletter for 2009. Thanks are due once again to the ACTRA Secretary John Frangos and the Meetings First Secretariat for putting together an interesting compilation of news and information about forthcoming events. 

 

ACTRA Register of toxicologists and risk assessment professionals

As previewed in the February 2009 e-Newsletter (with further details elsewhere in this current e-Newsletter), the ACTRA program to develop a Register of Toxicologists and Risk Assessors has been established. Listing on the Register will be restricted to ACTRA members who satisfy the Registration Tribunal of their credentials and its main purpose is to provide information on the professional standing of those ACTRA members who choose to seek registration. As such it will hopefully provide an accreditation process analogous to those by which overseas toxicological societies recognise professional achievements (e.g. DABT).    I would urge ACTRA members to consider making an application to be listed on the Register. Members should note that the process and fee structure for Registration is separate and distinct from the process of becoming a member of ACTRA.

 

Significant reviews of risk assessment methodology

As previewed in the February 2009 e-newsletter, the seminal reference for HRA methodology in Australia Environmental Health Risk Assessment: Guidelines for assessing human health risks from environmental hazards (enHealth 2004) is currently being reviewed and updated. The draft update is being prepared by the Australian Centre for Human Health Risk Assessment (ACHHRA) in conjunction with Toxikos Pty Ltd. Some of the critical areas where the document is being updated include an expanded Exposures Handbook, information on benchmark dose methodology and risk assessment for carcinogens. Watch out for announcements of consultative workshops outlining key elements of the update.

 

A separate process is also underway as part of the revision of the Assessment of Contaminated Sites NEPM. This process, which is being undertaken by a team from ERM, includes reviewing and updating HHRA methodology and the preparation of a new series of toxicological monographs on substances covered by the NEPM. The work is being overseen by the NHMRC and a NEPM review team.

 

It is likely that these two reviews will ultimately have significant impacts on HHRA practices in Australia.

 


ACTRA Annual Scientific Meeting (December 2009)

Following from the success of scheduling scientific papers for presentation by ACTRA members at the Annual General Meeting last November, the ACTRA Management Committee has decided to convene an Annual Scientific Meeting (ASM) in 2009.  The meeting will be held in Canberra at a venue to be announced shortly. It will most likely be held on either 4 or 5 December, in the margins of the Annual Scientific Meeting of the Australian Institute of Occupational Hygienists (AIOH). Pencil these dates into your diaries. ACTRA members are invited to contribute papers for oral presentation and to attend symposia sessions. Holding the ASM in Canberra should offer opportunities for greater engagement with Canberra-based regulators and ACTRA members are encouraged to lobby their regulatory colleagues to join ACTRA and attend the ASM. Please note that this year, the ASM will be on a separate date to ACTRA’s business meeting (AGM), which will be held in Adelaide on 26 September 2009.

 

Brian Priestly

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Asbestos Workshop 27th September 2009

As part of the 3rd International Contaminated Site Remediation Conference to be held at the Hilton Adelaide hotel, South Australia, 27–30 September.  ACTRA and CRCCARE are organising a pre-conference short course on Asbestos management in soil. The full day workshop will provide a scientific overview of the issues and health risks associated with asbestos in soil together with management strategies and case studies.   

 

To find out more or register for the workshop go to http://www.cleanupconference.com/welcome.htm

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ACTRA Annual General Meeting

Annual General Meeting will be held on 26 September in Adelaide. The meeting will be a dinner meeting and details will be made available as soon as possible.

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ACTRA Annual Scientific Meeting to be held in Canberra in early December

A one-day Annual Scientific Meeting will be held in early December. The time and venue will be announced shortly and members will be informed by email. The Scientific Programme Director for the meeting is Professor Brian Priestly (brian.priestly@med.monash.edu.au) who is seeking ideas for themes and  speakers. Don’t forget to:

 

-          Pencil in a trip to Canberra in early December as this will be an important opportunity for professional development and networking

-          Consider presenting a paper

-          Consider sponsoring the meeting

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ACTRA finalises Accreditation Process for Registration as a Toxicologist and Risk Assessor

ACTRA has finalised the procedural process for applicants and assessment of applications for the qualification as a Registered Australasian Toxicologist and Risk Assessor.

 

The qualification Registered Australasian Toxicologist and Risk Assessor shall be available to those Members who meet the required criteria. Application forms and qualification criteria can be obtained from the Secretariat (actra@meetingsfirst.com.au).  Applications will be assessed by the Registration Panel.

 

The Registration Panel (yet to be finalised) is to have at least 4 members, consisting of at least 2 members of the ACTRA Management Committee and at least 2 members of international standing in the field of toxicology and risk assessment appointed by the ACTRA Management Committee.

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Scientific articles of interest

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Environmental health risk assessment of nickel contamination of drinking water in a country town in NSW

A small country town in New South Wales (referred to as Sampleton) was supplied with drinking water sourced from a local surface water catchment until 2001. In 2002, due to drought conditions a decision was made by the local government authority to supplement this supply with extracted water from an underground mining operation. The water was treated before it was supplied as drinking water to the residents. Between 2002 and 2005, water samples recorded at Sampleton intermittently exceeded the Australian Drinking Water Guidelines (ADWG) value for nickel of 0.02 mg/L. This risk assessment was undertaken to assess the potential health risk associated with consumption of drinking water with an elevated nickel concentration…click here to read more

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Carcinogen dose response methodology

In September 1999 the National Health and Medical Research Council (NH&MRC) endorsed a dose response method for carcinogens in which no assumptions are made about the shape of the dose-response curve substantially outside the experimental range. The modified-BMD provides a reproducible, consistent starting point for derivation of Guideline Doses for carcinogens whether or not they possess genotoxic properties. On the 10th Anniversary of the NHMRC document (commonly referred to as the “Brown Book”) the findings of a soon to be published paper by Baiiley et al. (2009 in press) support the science policy approach taken at that time (see also article on the recent US NAS Risk Assessment Report that also supports such an approach)… click here to read more

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Why are 12% of SOT Members rating fructose as a health risk?

Non-alcoholic fatty liver disease (NAFLD) is present in up to one-third of the general population and in the majority of patients with metabolic risk factors such as obesity and diabetes. Insulin resistance is a key pathogenic factor resulting in hepatic fat accumulation. NAFLD is associated with an increased risk of all-cause death, probably because of complications of insulin resistance such as vascular disease (Adams et al 2005). The incidence of this disease is increasing in children…click here to read more

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Toxicology in the press

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Note from Editor:

The purpose of this regular feature in this newsletter, extracts from Australian media outlets where scientists have been interviewed on their research or concerns that may be of interest to ACTRA members. PLEASE CONTRIBUTE and/or share your thoughts.

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Indoor Air Pollutant levels (NOx) in NSW Schools

Wednesday, 27 May, 2009  12:38:00, The World Today - Delay in acting over toxic school heaters [This is the print version of story http://www.abc.net.au/worldtoday/content/2008/s2582028.htm]

Reporter: Simon Santow; Expert: Len Ferrari (NSW based consultant, air quality).

 

Extract:

To their critics, unflued gas heaters are dangerous and should be banned from all schools. But to others, it's a case of a scare-paign burying the truth. Whatever you believe, the New South Wales Education Department says it's taking seriously a report which shows that children are being exposed to dangerous levels of toxic gases in the classroom this winter. The department says it's doing further tests. But the delay in acting has angered some parents and experts who say the evidence is already there to ban the heaters from all New South Wales schools.

 

Submitted by John Frangos

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 Foetal Alcohol Syndrome / Neurodevelopmental toxicity

Editors Comment: Neurodevelopmental toxicity is an emerging discipline in toxicology. One of the reasons it is emerging at the present time is a growing research focus on brain development. The developing central nervous system appears to be especially susceptible to some substances and it is thought that functional changes can be induced at a lower exposure level than those resulting in toxicity in adults (Haas 2006)…click here to read more

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News from other organisations and members

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Society of Toxicology (SOT) Survey

A recent survey of 937 members of the Society of Toxicology (SOT) was administered online from Jan 27 to March 2, 2009 by Harris Interactive on behalf of the Statistical Assessment Service (STATS) and Center for Health and Risk Communication at George Mason University…click here to read more

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US EPA National Research Council – Report on Risk Assessment

A US National Research Council committee has developed scientific and technical recommendations for improving the risk analysis approaches used by the U.S. Environmental Protection Agency (EPA). The committee focused primarily on human health risk analysis but commented on the broad implications of its findings and recommendations to ecological risk analysis…click here to read more

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Managing Conflict of Interest and Public Policy

Gori (2009) has produced an insightful editorial in a recent issue of the journal Regulatory Toxicology and Pharmacology (v53 pg 159-160) on disclosure of conflict of interest and in particular the participation of scientists with industry affiliations in public policy formulation. This age old conundrum of improper influence versus utilising a limited pool of expertise for the public good is becoming increasing relevant as the pool of experienced scientists in the field of toxicology and environmental health risk assessment shrinks. The editorial makes several contentions/conclusions of merit…click here to read more

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Contributions by individual members and opinions expressed within these contributions are not intended to nor do they represent the views of the Australasian College of Toxicology and Risk Assessment.

 

Diary of events

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ACTRA is actively planning several meetings in 2009. Members will be informed of these as the details become available.  Details will be published in future e-news’ and on the website www.actra.org.au.

 

To view the diary of events, please click here.

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ACTRA Secretariat

Meetings First

4/184 Main Street

LILYDALE VIC 3140

 

Phone +61 3 9739 7697

Fax +61 3 9739 7076

Email actra@meetingsfirst.com.au